Worse case scenario: where both parents have been exposed (Risk is additive) is 171 in 1 million (or 2 in 10,000) which is 0.002% , 1 /100th of the general population risk
Note: These are additional risk factors to the general population rate of serious anatomic abnormalities in offspring which, in the West, is 200 - 300 in 10,000 or 2% to 3%
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