Conventional radiographic exam, and childhood cancer risk: Cohort study


Author: Janet

There is no increased childhood cancer risk, with very low dose radiation through diagnostic imaging, which is consistent with model calculations.

The study is available in American Journal of Roentgenology. The long-term consequences of diagnostic ionizing radiation exposure in childhood is slightly less known. Current evaluations are made with models obtained chiefly through research of survivors of atom bombs, people that vary from present-day patients in many aspects, and the preliminary research objective was to quantify risk amongst young patients through radiography exam.

In a German university hospital, cancer occurrence in children that underwent diagnostic x ray exposures during year 1976-2003 were assessed by the researchers. They reorganized case-by-case radiation dosage for each, and classified results by referral criteria groups for all cancers.

Through 78,527-patient cohort, in the duration of 1980-2006, about 68 cancer incidence cases were recognized, in the German childhood cancer registry: except for 25 other, 9 lymphoma, 28 leukemia, and 6 tumors of the central nervous system were found. For all the cancers, the standardized incidence ratio was 0.97; through multivariate poisson regression – dose response relationships were evaluated.

Even though cancer incidence risk varied by primary referral criterion for radiographic examination, for 5 patients with metabolic/endocrine disease, a positive dose response relationship was noted.

Conclusion: There was no heightened cancer risk amongst children/youth, with very low dose radiation through diagnostic imaging, which is consistent with model calculations. The increased usage of computed tomography justifies further studies to evaluate related cancer risk.

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