Risk-dosage relationship with patient age and size is feasible for effective planning and optimization of pediatric chest CT procedures.
Chest CT scans
The medical research study was conducted by Xiang Li, PhD, Ehsan Samei, PhD, W. Paul Segars, PhD, Gregory M. Sturgeon, BS, James G. Colsher, PhD and Donald P. Frush, MD from Department of Radiology, Duke University Medical Center, Durham, NC.
The study is available in online journal of Radiological Society of North America, and the research objective was to appraise cancer risks from pediatric CT scan and patient specific radiation dose, for evaluation of factors affecting dosage and risk, inclusive of CT scanning parameters, patient age and size etc.
HIPAA compliant, and approved by IRB (Institutional Review Board), about 30 patients (Age: 0-16 years) were selected with clinical CT data created recently through full body computer models. An approved Monte Carlo computational algorithms were utilized to evaluate organ dosage through eight CT chest protocols, staging clinically relevant combinations of bowtie filtration, collimation, pitch and optimal tube potential.
Organ dosage was utilized to ascertain effectual risk index and dosage; dosage and estimates of risk before/after normalized CT dose index were made to relate with patient age and size, along with effect of CT scanning parameters.
About the results, with increased chest diameter – normalized organ dose through with tube current modulation decreased in an exponential manner. Chest diameter was a strong predictor variable for dose than scan length/weight. Normalized by tube current modulation, CT dose index decreased in an exponential manner, with both chest age and diameter.
After normalization by dose length product – risk index and effectual dose were found free of tube potential, pitch and collimation.
Conclusion: The combined relation of risk and dosage with patient age and size can be utilized for patient specific dose and risk calculation, as they direct for effective planning and optimization of pediatric chest CT procedures.
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